ALT-GPT, also known as alanine aminotransferase or serum glutamic-pyruvic transaminase, is a vital enzyme mainly found in the liver. It plays a crucial role in breaking down proteins. When a blood test measures ALT levels, typically in units per liter (UI/l), it serves as an indicator of liver health. This enzyme is also present in smaller amounts in other body tissues, making it a significant marker for liver function tests.
ALT-GPT primarily exists in the liver, where it helps convert proteins into energy for the liver cells. It plays an essential role in the alanine cycle, which involves amino acids and the conversion of glucose, crucial for maintaining the body's metabolism. This enzyme is pivotal for ensuring that the liver functions properly by breaking down substances and aiding in the detoxification process. Healthy levels of ALT-GPT indicate that your liver is functioning well, processing nutrients, and removing toxins efficiently.
Having abnormal ALT-GPT levels can be a sign of liver damage or disease. Elevated levels are often associated with liver conditions such as hepatitis, fatty liver disease, or cirrhosis. High levels might also indicate liver inflammation or injury. While less common, low ALT-GPT levels can also occur, potentially indicating vitamin B6 deficiency or chronic kidney disease. It’s important to address any abnormal values by consulting with healthcare professionals to understand underlying issues and prevent further complications.
The typical range for ALT-GPT values is approximately 7 to 56 UI/L, though this can vary slightly depending on the laboratory and individual factors, such as age and sex. To maintain optimal ALT-GPT levels, focus on lifestyle habits that support liver health:
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