Gamma-Glutamyl Transferase (GGT) is an enzyme found in high levels in the liver, and is often measured in blood tests to assess liver health. It plays a crucial role in the body's metabolism. The results of a GGT test are typically expressed in Units per Liter (UI/L). Monitoring GGT levels is an important part of understanding liver function and overall health, as well as diagnosing liver diseases, bile duct issues, and even certain other conditions such as alcoholism.
The primary role of Gamma-Glutamyl Transferase (GGT) is to assist in the metabolism of glutathione and the transport of amino acids and peptides into cells, which is vital for maintaining cellular oxidative balance. As a key enzyme, GGT is essential for the body's detoxification processes, helping to break down and eliminate toxins, especially those encountered through drugs, alcohol, and environmental pollutants. Given its prominent presence in the liver and bile ducts, GGT is closely associated with digestive processes and liver health.
If GGT levels are higher than normal, it may indicate liver damage or disease. Elevated GGT levels can signal liver cirrhosis, hepatitis, alcoholic liver disease, bile duct obstruction, or heart failure. Elevated GGT levels are often seen in chronic alcohol use as well. Conversely, while low GGT levels are generally not a concern, they can sometimes suggest low risk for liver disease or that the body is functioning well. However, persistently abnormal GGT levels require medical evaluation to determine the underlying cause and appropriate interventions to address them.
Optimum GGT levels typically range from 0 to 51 UI/L in adults, although this can vary slightly depending on the laboratory standards. Maintaining healthy GGT levels necessitates a lifestyle that supports liver health. To improve or maintain optimal GGT levels, consider adopting the following habits:
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